Research Associate, Clinical Neurosciences, Cumming School of Medicine
University of Calgary
The Department of Clinical Neurosciences in the Cumming School of Medicine invites applications for a Research Associate. This Full-time Fixed Term position is for approximately 3 years (based on length of grant funding), with the possibility of extension.
This position reports to the Principal Investigator.
The applicant will be responsible for conducting independent experiments in the study of injury processes related to Stroke, Parkinson's disease, and Brain development. The applicant will have deep understanding of brain injury, particular the Cdk5-Jip-Notch pathway. They will perform both cultured and animal model experiments in brain injury and development with required skills in photothrombotic stroke, MPTP model of PD, and in utero electroporation. The applicant will also perform experiments involving complex molecular biology and gene delivery experiments with stereological analyses of brain injury.
The work environment is demanding and requires extensive experience in the field.
Summary of Key Responsibilities (job functions include but are not limited to):
- Under general supervision & direction of the PI, develop and implement original experiments within the guidelines of the research
- Conduct experiments related to Neuroscience in both cultured and animal models of Stroke and Parkinsons disease
- Conduct animal models of stroke and analyze through stereological methodology, loss of dopamine neurons in animal models of Parkinsons disease
- Perform in utero electroporation and analyses of neuronal migration in developing brains
- Generate viruses for gene delivery in vitro and in vivo
- Perform complex molecular biology and cell biology experiments related to brain injury in models of stroke, Parkinsons disease, and developmental processes
- Responsible for presentations in producing figures for publication
- Produce initial drafts of manuscripts for publication and appropriate scientific journals
- Conduct literature review, surveys, laboratory experiments and other research for us in scholarly publications when required to
- Reliable and safe operation of all laboratory equipment
- Trains other staff and students in the operation of equipment and laboratory protocols
- Establishes and maintains effective, productive relationships with staff, peers, immediate supervisor and senior management and with the campus community
- Manages own time effectively and ensures immediate reports to manager is kept informed of activities, and progress of work
- Demonstrated strong communication, team and customer service skills, and an ability to exercise judgment within established guidelines.
- Understanding of safety codes, standards, and systems related to specialization
Qualifications / Requirements:
- PhD degree in a Neurosciences required
- Minimum 3 years of post-doctoral experience in a relevant research area
- 1 to 3 years of related technical experience within the research specialty field of Neuroscience
- Direct and demonstrable research experience in the subject matter of the research project is essential. The applicant must have demonstrated ability to perform in vitro and in vivo models of brain injury in stroke, Parkinsons disease, and development
- Demonstrated experience in molecular biology, production of viruses, in utero electroporation for delivery of genes, cell biological skills, and demonstrated ability to perform and analyze brain injury models of stroke and Parkinsons disease through stereological methodology. These models include the MPTP and photothrombotic models of brain injury
- Demonstrated knowledge and experience in understanding brain development and brain injury (particularly in the area of Cdk5-Jip signaling)
- Demonstrated capacity for stereotaxic micro-injection particularly in the SNc of the brain
- Perform detailed design, documentation, and implementation of moderately complex technological systems as described above
- Demonstrated ability to troubleshoot complex technical experiments and change processes or procedures as required
- Knowledge of theory and practical application of technical procedures as described above
- Must be open to learning and development, and be willing to accept new challenges and assignments
- Operate and maintain complex technical equipment
- Demonstrated ability to work with animal models
- Demonstrated strong communication, team and customer service skills, and an ability to exercise judgment within established guidelines
- Knowledge of University core business systems is desirable
Application Deadline: April 30, 2018
All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority. In this connection, at the time of your application, please answer the following question: are you a Canadian citizen or a permanent resident of Canada? (Yes/No).
We would like to thank all applicants in advance for submitting their resumes. Please note, only those candidates chosen to continue on through the selection process will be contacted.
About the University of Calgary
The University of Calgary is Canada’s leading next-generation university – a living, growing and youthful institution that embraces change and opportunity with a can-do attitude. Located in the nation’s most enterprising city, the university is making tremendous progress on its Eyes High journey to be recognized as one of Canada’s top five research universities, grounded in innovative learning and teaching and fully integrated with the community it both serves and leads. The University of Calgary inspires and supports discovery, creativity and innovation across all disciplines. For more information, visit ucalgary.ca.
The University of Calgary recognizes that a diverse staff/faculty benefits and enriches the work, learning and research experiences of the entire campus and greater community. We are committed to removing barriers that have been historically encountered by some people in our society. We strive to recruit individuals who will further enhance our diversity and will support their professional success while they are here.
Quote Job Reference: 15079